In Vitro Fertilization via Blastocyst Culture

Posted on January 12, 2016 by MD

For women suffering recurrent pregnancy loss, a blastocyst culture and transfer procedure is capable of maximizing their chances of becoming pregnant while minimizing the risk of having a multiple pregnancy. A blastocyst culture and transfer differs from other in vitro methods because of the length of time embryos are cultured before being implanted into the uterus. In addition, embryologists can be more selective regarding their choice of advanced-stage embryos. This raises the potential for a successful implantation during transfer.

What is a Blastocyst Culture?

Blastocysts are developed embryos that have divided repeatedly and are almost ready for implantation onto the uterine wall. An advanced blastocyst culture offers high rates of allowing a pregnancy to complete because the blastocyst has survived beyond the initial critical stage of day three. Surviving beyond day three is important, since it is at this time the embryo actually activates its own genetic material instead of relying on the maternal egg for sustenance. Embryos emerging from a blastocyst culture are stronger, healthier and exhibit higher probabilities for survival. ### 4 Stages of Blastocyst Culture Development

1. Morula
Morula are cells from three-day-old embryos that have compacted and lost their singular appearance.

2. Early Blastocyst
Early blastocyst culture cells have formed an inner cell mass and an exterior layer of cells called the trophectoderm.

3. Full Blastocyst/Expanded Blastocyst
Full blastocysts with visibly healthy, inner cell masses can be frozen at this point.

4. Hatching Blastocyst
The end stage of growth before implantation, the hatching blastocyst leaves its "shell" to prepare for uterine implantation.

Who are Good Candidates for Blastocyst Culture and Transfer?

Blastocyst culture transfer and implantation may be appropriate for women who are determined by their doctor to present good chances for development of a blastocyst (depending on their age and reasons for infertility). Women who are concerned about having a multiple pregnancy or are diagnosed with recurring pregnancy loss may also enjoy success with a blastocyst culture and transfer.

Our New York Fertility Clinic Offers Blastocyst Culture and Transfer

Consulting one of our specialists about whether blastocyst culture and transfer may be a good option for you is the first step towards overcoming fertility issues. Contact us today to learn more about this cutting-edge technology or to schedule a consultation with one of our knowledgeable fertility professionals.



American Society for Reproductive Medicine
College of American Pathologists
Fertile Hope
Society for Assisted Reproductive Technology
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