Recurrent Miscarriage

Recurrent Pregnancy Loss (RPL)

Recurrent pregnancy loss (RPL) afflicts 2-4% of reproductive-aged women and is defined as two or more pregnancy losses. A thorough evaluation is required to diagnose the cause of RPL. Causes include:
Immune factors

  • Anatomic factors (e.g. abnormalities in the anatomy of the uterus)
  • Genetic factors, in a woman, her male partner, or the fetus
  • Endocrine factors (e.g. thyroid disease, diabetes),
  • Thrombophilia factors (i.e. blood clotting disorders),
  • Immune Factors (e.g. Antiphospholipid Antibody Syndrome)
  • Environmental factors, which may be found at work, at home or following certain medical procedures
  • Lifestyle issues (e.g. tobacco use or heavy alcohol use)
  • Infections
Connect with New York Reproductive Wellness


American Society for Reproductive Medicine
College of American Pathologists
Fertile Hope
Society for Assisted Reproductive Technology
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